Rhine Main region

The Rhine Main region is one of the 11 metropolitan regions in Germany and is named after the two rivers Rhine and Main. It spans the three federal states of Hessen, Rhineland-Palatinate (Rhinehessen), and Bavaria (Lower Franconia). Although the metropolitan area has no clear-cut limits, its population is an estimated 5.5 million. 

Due to its central and easily accessible location the Rhine Main area was an economically powerful region as early as industrial times in the 19th century. Frankfurt is the home of the headquarters of many renowned companies, e.g. the European Central Bank and the Frankfurt Stock Exchange. 

The most important economic and political cities are Frankfurt am Main (banking metropolis), Wiesbaden (state capital of Hessen), Mainz (state capital of Rhineland-Palatinate), and Darmstadt (City of Science).